Genesis Global Group
Ingenio Diagnostics
GD3

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Ingenio Diagnostics is a proud member of Genesis Drug Discovery & Development (GD3), a fully integrated CRO providing services to support drug discovery programs of our clients from target discovery through IND filing and managing Phase I-III clinical trials.

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SERVICES

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Expert analysis at any stage

Our state-of-the-art histology laboratories are equipped for all types of tissues to accommodate various analyses. They are staffed with expert scientists, technicians, and board-certified pathologists in anatomic pathology. We can support every stage of the tissue analysis process, from sample processing to staining and pathological analysis. Our staff of 8 experienced histologists and several technicians ensure client samples are optimally prepared for downstream analysis and interpretation by a licensed pathologist. We can adapt our flexible protocols to meet the unique staining requirements of a wide variety of studies utilizing fresh, frozen, or FFPE tissues.

Types of Tissue Processing Include:

  • Frozen Tissue sections
  • Formalin-fixed paraffin-embedded (FFPE) tissue sections - Formalin is used to preserve the tissue from degradation and maintain cells’ structure. Dehydration, clearance, and infiltration with an embedding matrix (paraffin wax) occur for sectioning and slide preparation as well as long-term preservation for archival purposes.

Histochemistry Staining Methods

Our state-of-the-art histology laboratories are equipped for all types of tissues to accommodate various analyses. They are staffed with expert scientists, technicians, and board-certified pathologists in anatomic pathology. We can support every stage of the tissue analysis process, from sample processing to staining and pathological analysis. Our staff of 8 experienced histologists and several technicians ensure client samples are optimally prepared for downstream analysis and interpretation by a licensed pathologist. We can adapt our flexible protocols to meet the unique staining requirements of a wide variety of studies utilizing fresh, frozen, or FFPE tissues.

Areas of clinical practice expertise include:

  • Surgical Pathology
  • Podiatric
  • Dermatopathology
  • Urologic
  • Gastrointestinal
  • Breast
  • Gynecologic
  • Molecular Genetic Pathology
  • Bone and soft tissue
  • Pap tests
  • Full range of nongynecological cytopathology, including anal Paps

Capabilities include:

  • An extensive network of board-certified pathologists and experienced histotechnicians
  • Over 25 validated immunohistochemistry stains
  • Over 12 validated special stains
Histochemistry Stain

Validated Immunohistochemistry (IHC) Stains Available:

  • Anti-pan Keratin (also known as Anti-cytokeratin, Multi-cytokeratin, or AE1/AE3)
  • Calponin-1
  • Cam5.2
  • CD138
  • CD20
  • CD3
  • CD34
  • CD45 (also known as LCA)
  • CD68
  • Chromogranin
  • CK20
  • CK7
  • CK5/6
  • Desmin
  • ER
  • E-cadherin
  • Gata 3
  • HER2
  • HMB45
  • KI67
  • Melan A
  • P16
  • P53
  • P63
  • PR
  • S100
  • SMA (Smooth Muscle Actin)
  • Sox-10
  • Synaptophysin

Validated Special Stains Include:

  • PAS-Fungus
  • Grocott’s Methenamine Silver (GMS)
  • Acid Fast Bacillus (AFB)
  • Colloidal Iron stain
  • Schmorls stain
  • Periodic Acid Shiffs (PAS)
  • Alcian Blue PAS
  • Fite Stain
  • Fontana-Masson Trichrome stain
  • Congo Red
  • Elastic Stain
  • Diff-Quick